Also Known As:
Angelica sinensis, Chinese Angelica, Dang Gui.
People Use This For:
Orally, dong quai is used for painful periods, premenstrual
syndrome (PMS), and
menopausal symptoms. It is also used orally as a "blood
purifier"; to manage
high blood pressure, infertility, rheumatism, ulcers, anemia, and
in the prevention and treatment of allergic attacks. Dong quai is
also used orally
is for the treatment of skin depigmentation and psoriasis.
No converns regarding safety when used orally and appropriately.
has been safely used in a clinical trial lasting up to 24
weeks.34 More scientific
evidence is needed to determine its safety after prolonged,
Pregnancy and Lactation: Refer to a Medical Herbalist.
Men suffering from premature ejaculation who were treated with
the cream had
significantly improved ejaculatory latency compared to placebo.35
Menopausal symptoms. Dong quai does not seem to have any effect
endometrial wall thickness or menopausal symptoms.34
There is insufficient reliable information available about the
effectiveness of dong
quai for its other uses.
Mechanism of Action:
The applicable part of dong quai is the root. Dong quai root has
constituents. Some of these include ferulic acid, ligusticide,
A, butylphthalide, nicotinic acid, and succinic acid.36,37 Dong
quai root contains a
variety of other constituents. The dong quai root also contains
and minerals including vitamin A, carotenoids, vitamin E, vitamin
B12, biotin, folic acid, calcium, magnesium, and phytosterols
such as beta-
sitosterol.37 It also contains 0.4% to 0.7% volatile oil.38,37
Dong quai also contains several coumarin
constituents.38,37 Some coumarins can act as
vasodilators and antispasmodics.
Dong quai is well-tolerated.34
Interactions with Drugs:
Warfarin (Coumadin): Refer to a Medical Herbalist.
Interactions with Foods:
Interactions with Diseases or Conditions:
Breast Cancer: Refer to a Medical Herbalist.
Hormone Sensitive Cancers/Conditions: Refer to a Medical
Surgery: Tell patients to discontinue dong quai at least 2 weeks
before elective surgical procedures.
Oral: For menopausal symptoms, 4.5 g of powdered Dong Quai root
has been used daily.34
Specific References: DONG QUAI
34. Hirata JD, Swiersz LM, Zell B, et al. Does dong quai
have estrogenic effects in postmenopausal women? A double-blind,
placebo-controlled trial. Fertil Steril 1997;68:981-6.
35. Choi HK, Jung GW, Moon KH, et al. Clinical study of
SS-Cream in patients with lifelong premature ejaculation. Urology
36. Zhao KJ, Dong TT, Tu PF, et al. Molecular genetic and
chemical assessment of radix Angelica (Danggui) in China. J Agric
Food Chem 2003;51:2576-83.
37. Monograph. Angelica sinensis (Dong quai). Altern Med
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